Vol. 2, Issue 2, Part A (2025)

Cardiovascular diseases (CVDs) are the leading cause of death globally, with oxidative stress and chronic inflammation recognized as central mechanisms in their pathogenesis. This paper explores the therapeutic potential of Pranayama (controlled breathing) as an adjunct to conventional treatment for CVDs. Pranayama practices, such as Nadi Shodhana and Bhramari, are examined for their ability to modulate key physiological factors particularly oxidative stress, inflammation, and autonomic nervous system (ANS) function critical to cardiovascular health. Drawing upon both modern scientific findings and Ayurvedic principles, the paper investigates how Pranayama influences heart rate variability (HRV), enhances antioxidant defenses, and reduces pro-inflammatory cytokines like C-reactive protein (CRP) and Interleukin-6 (IL-6). The study also integrates Ayurvedic concepts, emphasizing the regulation of the Doshas (Vata, Pitta, Kapha) and their role in maintaining heart health. By examining the impact of Pranayama on oxidative stress markers such as Malondialdehyde (MDA) and its contribution to overall cardiovascular function, this paper provides an evidence-based framework for incorporating Pranayama into modern cardiovascular care. The findings highlight Pranayama as an effective, non-pharmacological intervention for both prevention and management of CVDs, offering a holistic approach to cardiovascular health rooted in ancient wisdom and supported by contemporary research.